منابع مشابه
Rare non-Wilms' tumors in children
We report our institutional experience of the management of 2 cases of rare non-Wilms' tumors; a rhabdoid tumor in a 17-month old boy and a clear cell sarcoma in a 5-year old girl. The two patients were treated with ifosfamide/carboplatin/etoposide (ICE) alternating with vincristine/doxorubicin/cyclophosphamide (VDC) and cyclophosphamide/etoposide (CE) alternating with vincristine/doxorubicin/c...
متن کاملWT1 splicing alterations in Wilms' tumors.
Hereditary and sporadic forms of tumors are generally related to germ-line and somatic mutations of the same tumor suppressor gene. Unexpectedly, in Wilms' tumor, somatic mutations of the WT1 gene were found only occasionally in sporadic cases, although constitutional mutations of this gene are clearly associated with predisposition. It has been suggested that abnormal splicing may be another m...
متن کاملTherapeutic results in stage I Wilms’ tumors in children – 15 years of surgical experience
INTRODUCTION Progress in the therapeutic management of Wilms' tumors (WT) in children has resulted in the fact that presently, almost all children with stage I and favorable histology diseases have a chance for a cure. THE AIM OF THE STUDY The objective of the report is an analysis of therapeutic results in children with unilateral stage I Wilms' tumors depending on the extent of tumor resect...
متن کاملExtra-Renal Wilms' Tumor: A Rare Diagnosis
The diagnosis of extra-renal Wilms' tumor is often missed at initial clinical presentation leading to a delay in initiating appropriate therapy. A 5-year-old girl presented with a 3-week history of a painless lump in the pelvis. Radiological investigations suggested an ovarian neoplasm. Tumor markers for ovarian malignancy were in normal range. Trucut biopsy also suggested the possibility of an...
متن کاملLINking microRNAs, kidney development, and Wilms tumors.
In this issue of Genes & Development, Urbach and colleagues (pp. 971-982) provide compelling data suggesting a role for LIN28 in the pathogenesis of a significant percentage of Wilms tumors. These data extend our insights in the genetics underlying Wilms tumor development and emphasize the importance of stemness and microRNA-mediated processes in the origins of these tumors.
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ژورنال
عنوان ژورنال: Rare Tumors
سال: 2012
ISSN: 2036-3613,2036-3613
DOI: 10.4081/rt.2012.e6